Hypoxylon Canker (Hypoxylon tinctor) - Hypoxylon canker is a fungus that causes cankers and death of oak and other hardwood trees. The disease is common in East Texas and all across the southern United States. Relatively healthy trees are not invaded by the fungus, but the hypoxylon fungus will readily infect the sapwood of a tree that has been damaged, stressed, or weakened. Natural and man-caused factors that can weaken a tree include defoliation by insects or leaf fungi, saturated soil, fill dirt, soil compaction, excavation in the root zone of the tree, removal of top soil under the tree, disease, herbicide injury, drought, heat, nutrient deficiencies, competition or overcrowding, and other factors. The hypoxylon fungus is considered a weak pathogen in that it is not aggressive enough to invade healthy trees. In addition to the hypoxylon fungus, weakened and stressed trees may become susceptible to a host of other insect and disease pests.